Vilniaus Street, like Tilžės Street, was built in the 18th century. It is a historical key that leads from east to west or vice versa, just like Tilžės street – from south to north.

In the 20th century, during the reconstruction and development of the city that was severely damaged during the First World War, Vilniaus Street was full of expressive modernist buildings. Many of the 2 – 4 storey brick buildings on Vilniaus Street (from Tilžės Street to Didždvaris Gymnasium) have survived to this day.